Title : High-Dose Dexmedetomidine Promotes Apoptosis in Fetal Rat Hippocampal Neurons.

Pub. Date : 2021

PMID : 34135573






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Results: High concentrations of DEX (>=100 muM) significantly reduced cell viability, induced neuronal apoptosis, upregulated the protein expression of cleaved caspase 3, Bax, cleaved caspase 9, and Cyt-c. DEX also considerably promoted the release of ROS. Dexmedetomidine caspase 9 Rattus norvegicus
2 Results: High concentrations of DEX (>=100 muM) significantly reduced cell viability, induced neuronal apoptosis, upregulated the protein expression of cleaved caspase 3, Bax, cleaved caspase 9, and Cyt-c. DEX also considerably promoted the release of ROS. Dexmedetomidine caspase 9 Rattus norvegicus