Title : The α2AR/Caveolin-1/p38MAPK/NF-κB axis explains dexmedetomidine protection against lung injury following intestinal ischaemia-reperfusion.

Pub. Date : 2021 Jun 10

PMID : 34114328






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The alpha2AR/Caveolin-1/p38MAPK/NF-kappaB axis explains dexmedetomidine protection against lung injury following intestinal ischaemia-reperfusion. Dexmedetomidine caveolin 1 Rattus norvegicus
2 Specifically, Dex promoted Cav-1 expression via alpha2A -AR activation and mitigated intestinal I/R-induced lung injury, even in the presence of Atipamezole. Dexmedetomidine caveolin 1 Rattus norvegicus
3 Dex can alleviate pulmonary inflammation after in intestinal I/R by promoting Cav-1 to inhibit the activation of p38 and NF-kappaB. Dexmedetomidine caveolin 1 Rattus norvegicus