Pub. Date : 2022 Mar
PMID : 34103690
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rg1 exerts protective effect in CPZ-induced demyelination mouse model via inhibiting CXCL10-mediated glial response. | Cuprizone | chemokine (C-X-C motif) ligand 10 | Mus musculus |
| 2 | In CPZ-induced demyelination mouse model, injection of AAV-CXCL10 shRNA into mouse lateral ventricles 3 weeks prior CPZ treatment occluded the beneficial effects of Rg1 administration in behavioral and pathological assays. | Cuprizone | chemokine (C-X-C motif) ligand 10 | Mus musculus |
| 3 | In conclusion, CXCL10 mediates the protective role of Rg1 in CPZ-induced demyelination mouse model. | Cuprizone | chemokine (C-X-C motif) ligand 10 | Mus musculus |