Pub. Date : 2021 Aug 11
PMID : 34102646
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our previous study demonstrated that the activity of protein phosphatase 2A (PP2A) and the level of phosphorylated extracellular signal-related kinase 1/2 (p-ERK 1/2) are increased in the caudate putamen (CPu) of METH-sensitive mice. | Methamphetamine | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | Mus musculus |
| 2 | Our previous study demonstrated that the activity of protein phosphatase 2A (PP2A) and the level of phosphorylated extracellular signal-related kinase 1/2 (p-ERK 1/2) are increased in the caudate putamen (CPu) of METH-sensitive mice. | Methamphetamine | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | Mus musculus |
| 3 | Taken together, these results indicate that PP2A plays an important role in METH-induced behavioral sensitization and phosphorylates ERK 1/2 by dephosphorylating p-Raf1 in the CPu to further regulate METH-induced behavioral sensitization. | Methamphetamine | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | Mus musculus |
| 4 | Taken together, these results indicate that PP2A plays an important role in METH-induced behavioral sensitization and phosphorylates ERK 1/2 by dephosphorylating p-Raf1 in the CPu to further regulate METH-induced behavioral sensitization. | Methamphetamine | protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform | Mus musculus |