Title : IDH Inhibitors and Beyond: The Cornerstone of Targeted Glioma Treatment.

Pub. Date : 2021 Jul

PMID : 34095989






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 IDH mutations induce a neomorphic enzyme that converts alpha-ketoglutarate to the oncometabolite D-2-hydroxyglutarate, which leads to widespread effects on cellular epigenetics and metabolism. Ketoglutaric Acids isocitrate dehydrogenase (NADP(+)) 1 Homo sapiens