Title : Concentration differences in isoforms of transferrin in blood from alcoholics during abuse and abstinence.

Pub. Date : 1988 Jul 15

PMID : 3409533






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 These transferrin forms differ in the carbohydrate parts, especially the amount of sialic acid. N-Acetylneuraminic Acid transferrin Homo sapiens
2 However, in alcoholics during abstinence the newly formed transferrin has a higher sialic acid content than most of the transferrin already present in the blood. N-Acetylneuraminic Acid transferrin Homo sapiens
3 This indicates that the elevated concentration of Tf5.7 with a low sialic acid content, found in alcoholics is not due to a defect at sialylation, but most probably caused by an impaired uptake of sialic acid-deficient transferrin by the hepatocytes due to membrane dysfunction. N-Acetylneuraminic Acid transferrin Homo sapiens