Title : Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade.

Pub. Date : 2021 Jun 6

PMID : 34092233






1 Functional Relationships(s)
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1 Treatment with either dabrafenib and trametinib or with RGS, increased CD40+SOX10+ melanoma cells in the tumors of melanoma patients and patient-derived xenografts. dabrafenib CD40 molecule Homo sapiens