Title : Blockade of IDO-Kynurenine-AhR Axis Ameliorated Colitis-Associated Colon Cancer via Inhibiting Immune Tolerance.

Pub. Date : 2021

PMID : 34087454






1 Functional Relationships(s)
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1 Additionally, comparing to WT mice, IDO-/- mice treated with AOM/DSS exhibited fewer and smaller tumor burdens in colon, with less Treg and more CD8+ T cells infiltration, while Kyn administration abolished this regulation. treg indoleamine 2,3-dioxygenase 1 Mus musculus