Pub. Date : 2021 Oct
PMID : 34087410
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Calcitriol (1,25-dihydroxyvitamin D3) and retinoic acid possess hormone-like properties and are the bioactive metabolites of vitamin D and A, respectively, that signal through heterodimers containing the common retinoid X receptor. | Tretinoin | retinoid X receptor alpha | Homo sapiens |
| 2 | Importantly, retinoic acid negated the effect of calcitriol and impaired the binding of VDR on the Il9 gene by dampened VDR-RXR formation. | Tretinoin | retinoid X receptor alpha | Homo sapiens |