Title : Iron-loaded transferrin potentiates erythropoietin effects on erythroblast proliferation and survival: a novel role through transferrin receptors.

Pub. Date : 2021 Jul

PMID : 34077792






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1 Iron-loaded transferrin potentiates erythropoietin effects on erythroblast proliferation and survival: A novel role through transferrin receptors. Iron erythropoietin Homo sapiens
2 Using an Epo-sensitive UT-7 (UT7/Epo) erythroid cell and human erythroid progenitor cell models, we report that iron-loaded transferrin, i.e., holo-transferrin (holo-Tf), synergizes with suboptimal Epo levels to improve erythroid cell survival, proliferation, and differentiation. Iron erythropoietin Homo sapiens