Title : Computational and experimental studies on the inhibitory mechanism of hydroxychloroquine on hERG.

Pub. Date : 2021 Jun 30

PMID : 34058295






2 Functional Relationships(s)
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1 Computational and experimental studies on the inhibitory mechanism of hydroxychloroquine on hERG. Hydroxychloroquine ETS transcription factor ERG Homo sapiens
2 Molecular docking and patch clamp experiments showed that HCQ could bind to hERG and inhibit the efflux of potassium ion preferentially in the repolarization stage. Hydroxychloroquine ETS transcription factor ERG Homo sapiens