Title : LncRNA WDFY3-AS2 promotes cisplatin resistance and the cancer stem cell in ovarian cancer by regulating hsa-miR-139-5p/SDC4 axis.

Pub. Date : 2021 May 29

PMID : 34051810






5 Functional Relationships(s)
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1 LncRNA WDFY3-AS2 promotes cisplatin resistance and the cancer stem cell in ovarian cancer by regulating hsa-miR-139-5p/SDC4 axis. Cisplatin WD repeat and FYVE domain containing 3 Mus musculus
2 Herein, we explored the function of lncRNA WDFY3-AS2 in OC cell resistance to cisplatin (DDP). Cisplatin WD repeat and FYVE domain containing 3 Mus musculus
3 Herein, we explored the function of lncRNA WDFY3-AS2 in OC cell resistance to cisplatin (DDP). Cisplatin WD repeat and FYVE domain containing 3 Mus musculus
4 Furthermore, xenograft tumor in nude mice was used to assess the impact of WDFY3-AS2 on cisplatin resistance in OC in vivo. Cisplatin WD repeat and FYVE domain containing 3 Mus musculus
5 CONCLUSIONS: Together, WDFY3-AS2 may lead to change of cisplatin resistance by the expression of miR-139-5p/SDC4 in the OC A2870-DDP cells both in vitro and in vivo. Cisplatin WD repeat and FYVE domain containing 3 Mus musculus