Title : Potential of therapeutic bile acids in the treatment of neonatal Hyperbilirubinemia.

Pub. Date : 2021 May 27

PMID : 34045606






1 Functional Relationships(s)
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1 Here we investigated the potential of therapeutic bile acids ursodeoxycholic acid (UDCA) and obeticholic acid (OCA, 6-alpha-ethyl-CDCA), a farnesoid-X-receptor (FXR) agonist, as preventive treatment options for neonatal hyperbilirubinemia using the hUGT1*1 humanized mice and Ugt1a-deficient Gunn rats. obeticholic acid nuclear receptor subfamily 1, group H, member 4 Mus musculus