Pub. Date : 2021 Aug 15
PMID : 34044017
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | YAP/STAT3 promotes the immune escape of larynx carcinoma by activating VEGFR1-TGFbeta signaling to facilitate PD-L1 expression in M2-like TAMs. | Tamoxifen | signal transducer and activator of transcription 3 | Mus musculus |
| 2 | We revealed that dysregulated YAP/STAT3 activity in LC cells could enhance the secretion of VEGF, which then functioned on M2-like TAMs via activating VEGFR1-TGFbetabeta pathway to promote the expression of PD-L1 and immunosuppressive function of M2-like TAMs. | Tamoxifen | signal transducer and activator of transcription 3 | Mus musculus |
| 3 | We revealed that dysregulated YAP/STAT3 activity in LC cells could enhance the secretion of VEGF, which then functioned on M2-like TAMs via activating VEGFR1-TGFbetabeta pathway to promote the expression of PD-L1 and immunosuppressive function of M2-like TAMs. | Tamoxifen | signal transducer and activator of transcription 3 | Mus musculus |