Title : Histidine dipeptides are key regulators of excitation-contraction coupling in cardiac muscle: Evidence from a novel CARNS1 knockout rat model.

Pub. Date : 2021 Aug

PMID : 34038814






1 Functional Relationships(s)
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1 CARNS1-/- resulted in the complete absence of carnosine and anserine, but it did not affect exercise capacity, skeletal muscle force production, fatigability or buffering capacity in vitro, indicating that these are not essential for pH regulation and function in skeletal muscle. Anserine carnosine synthase 1 Rattus norvegicus