Pub. Date : 2021 Jun 25
PMID : 34036307
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Erianin Induces Triple-Negative Breast Cancer Cells Apoptosis by Activating PI3K/Akt Pathway. | Erianin | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Furthermore, p-PI3K and p-Akt expression were downregulated by erianin. | Erianin | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | After co-incubation with SC79, the cell inhibition rate of erianin was decreased, which further confirmed that the attenuated PI3K/Akt pathway was relevant to the pro-apoptotic effect of erianin. | Erianin | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | CONCLUSIONS: Erianin can inhibit the proliferation of TNBC cells and induce cell cycle arrest and apoptosis, which may ascribe to the abolish the activation of the PI3K/Akt pathway. | Erianin | AKT serine/threonine kinase 1 | Homo sapiens |