Pub. Date : 2021
PMID : 34035828
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Further analysis showed that the HGD activity of quercetin, formononetin, kaempferol, isorhamnetin, and beta-sitosterol ingredients is possible through VEGFA, IL6, TNF, AKT1, and TP53 targets involved in TNF, toll-like receptors, and MAPK-related pathways, which have anti-inflammatory, antiapoptosis, antioxidation, and autophagy effects, relieve renal fibrosis and renal cortex injury, and improve renal function, thus delaying the development of DN. | Quercetin | tumor protein p53 | Homo sapiens |
2 | The molecular docking results showed that quercetin, formononetin, kaempferol, isorhamnetin, beta-sitosterol had a good binding activity with VEGFA, IL6, TNF, AKT1, and TP53. | Quercetin | tumor protein p53 | Homo sapiens |