Title : Inhibition mechanism of SARS-CoV-2 main protease by ebselen and its derivatives.

Pub. Date : 2021 May 24

PMID : 34031399






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 An organoselenium drug called ebselen has been demonstrated to have potent Mpro inhibition and antiviral activity. ebselen NEWENTRY Severe acute respiratory syndrome-related coronavirus
2 We have examined the binding modes of ebselen and its derivative in Mpro via high resolution co-crystallography and investigated their chemical reactivity via mass spectrometry. ebselen NEWENTRY Severe acute respiratory syndrome-related coronavirus