Title : Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.

Pub. Date : 2021 Jul

PMID : 34029971






1 Functional Relationships(s)
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1 Conjugates were moderate inhibitors of equine and human BChE with negligible fluctuation in anti-BChE activity, whereas anti-AChE activity was substantially dependent on N4-substitution of the piperazine ring. Piperazine acetylcholinesterase (Cartwright blood group) Homo sapiens