Pub. Date : 2021 Aug
PMID : 34027562
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP2D6 phenotype explains reported yohimbine concentrations in four severe acute intoxications. | Yohimbine | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 2 | We used recently reported knowledge on the metabolism of yohimbine together with state-of-the art nonlinear mixed-effects modelling and simulation and show that a patient"s cytochrome P450 2D6 (CYP2D6) phenotype can explain the large differences observed in the measured concentration after intake of the same yohimbine dose. | Yohimbine | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 3 | We used recently reported knowledge on the metabolism of yohimbine together with state-of-the art nonlinear mixed-effects modelling and simulation and show that a patient"s cytochrome P450 2D6 (CYP2D6) phenotype can explain the large differences observed in the measured concentration after intake of the same yohimbine dose. | Yohimbine | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 4 | We used recently reported knowledge on the metabolism of yohimbine together with state-of-the art nonlinear mixed-effects modelling and simulation and show that a patient"s cytochrome P450 2D6 (CYP2D6) phenotype can explain the large differences observed in the measured concentration after intake of the same yohimbine dose. | Yohimbine | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |
| 5 | We used recently reported knowledge on the metabolism of yohimbine together with state-of-the art nonlinear mixed-effects modelling and simulation and show that a patient"s cytochrome P450 2D6 (CYP2D6) phenotype can explain the large differences observed in the measured concentration after intake of the same yohimbine dose. | Yohimbine | cytochrome P450 family 2 subfamily D member 6 | Homo sapiens |