Title : Does iron overload in metabolic syndrome affect macrophage profile? A case control study.

Pub. Date : 2021 Sep

PMID : 34022567






3 Functional Relationships(s)
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1 Several genes of iron metabolism presented a higher expression in DIOS vs MetS: SCL11A2 (a free iron transporter, +76 %, p = 0.04), SOD1 (an antioxidant enzyme, +27 %, p = 0.02), and TFRC (the receptor 1 of transferrin, +59 %, p = 0.003). Iron transferrin receptor Homo sapiens
2 The up regulation of transferrin receptor 1 (TFRC) in DIOS macrophages suggests an adaptive role that may limit iron toxicity in DIOS. Iron transferrin receptor Homo sapiens
3 The up regulation of transferrin receptor 1 (TFRC) in DIOS macrophages suggests an adaptive role that may limit iron toxicity in DIOS. Iron transferrin receptor Homo sapiens