Title : Zeb1 induces immune checkpoints to form an immunosuppressive envelope around invading cancer cells.

Pub. Date : 2021 May

PMID : 34020945






1 Functional Relationships(s)
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1 We show that Zeb1 links these two resistance pathways because it is required for PDL1 expression on invading lung cancer cells, and it also induces CD47 on these invading cells, which drives M2 polarization of adjacent TAMs. tams CD47 molecule Homo sapiens