Title : Energy Landscape of the SARS-CoV-2 Reveals Extensive Conformational Heterogeneity.

Pub. Date : 2021 May 12

PMID : 34013265






1 Functional Relationships(s)
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1 A local analysis of seven key binding pockets reveals that six out them, including those for engaging ACE2, therapeutic mini-proteins, linoleic acid, two different kinds of antibodies, and protein-glycan interaction sites, switch conformations between their known apo- and holo-conformations, even when the global spike conformation is 1RBD-up. Polysaccharides surface glycoprotein Severe acute respiratory syndrome coronavirus 2