Title : Ku70 suppresses alternative end joining in G1-arrested progenitor B cells.

Pub. Date : 2021 May 25

PMID : 34006647






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Complexes containing the Ku70/80 ("Ku") and XRCC4/ligase IV (Lig4) core C-NHEJ factors are required, respectively, for sensing and joining DSBs. dsbs X-ray repair cross complementing 4 Homo sapiens
2 Restriction of V(D)J recombination by XRCC4/Lig4-mediated joining has been attributed to RAG shepherding V(D)J DSBs exclusively into the C-NHEJ pathway. dsbs X-ray repair cross complementing 4 Homo sapiens