Title : Design and synthesis of novel substituted benzyl pyrrolopyrimidine derivatives as selective BTK inhibitors for treating mantle cell lymphoma.

Pub. Date : 2021 Jul

PMID : 34000704






1 Functional Relationships(s)
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1 Although ibrutinib exhibited excellent antitumor activity, it was associated with certain adverse reactions, with off-target effects against EGFR, Itk and Src family kinases. ibrutinib IL2 inducible T cell kinase Homo sapiens