Pub. Date : 2021 Jun
PMID : 33994201
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | TIGAR mitigates atherosclerosis by promoting cholesterol efflux from macrophages. | Cholesterol | Trp53 induced glycolysis regulatory phosphatase | Mus musculus |
| 2 | Silencing of TIGAR impaired cholesterol efflux and down-regulated the expression of ATP-binding cassette transporter A1 (ABCA1) and ABCG1 by interfering with liver X receptor alpha (LXRalpha) expression and activity, but did not influence cholesterol uptake by macrophages. | Cholesterol | Trp53 induced glycolysis regulatory phosphatase | Mus musculus |
| 3 | Silencing of TIGAR impaired cholesterol efflux and down-regulated the expression of ATP-binding cassette transporter A1 (ABCA1) and ABCG1 by interfering with liver X receptor alpha (LXRalpha) expression and activity, but did not influence cholesterol uptake by macrophages. | Cholesterol | Trp53 induced glycolysis regulatory phosphatase | Mus musculus |