Title : Hyperglycemia minimally alters primary self-renewing human colonic epithelial cells while TNFα-promotes severe intestinal epithelial dysfunction.

Pub. Date : 2021 Jun 15

PMID : 33989405






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TNFalpha measurably increased secretion of IL-8 and IL-1beta, which was enhanced at 60 mM glucose. Glucose tumor necrosis factor Homo sapiens
2 When TNFalpha hyperglycemia and <=30 mM glucose and were combined, MUC2 and ALP activity remained similar to that of TNFalpha alone, although synergistic effects were seen at 60 mM glucose. Glucose tumor necrosis factor Homo sapiens