Title : BEZ235 Increases the Sensitivity of Hepatocellular Carcinoma to Sorafenib by Inhibiting PI3K/AKT/mTOR and Inducing Autophagy.

Pub. Date : 2021

PMID : 33987439






3 Functional Relationships(s)
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1 BEZ235 Increases the Sensitivity of Hepatocellular Carcinoma to Sorafenib by Inhibiting PI3K/AKT/mTOR and Inducing Autophagy. Sorafenib AKT serine/threonine kinase 1 Homo sapiens
2 SFB + BEZ inhibited the activation of the PI3K/AKT/mTOR pathway caused by sorafenib. Sorafenib AKT serine/threonine kinase 1 Homo sapiens
3 We concluded that BEZ235 enhanced the sensitivity of sorafenib through suppressing the PI3K/AKT/mTOR pathway and inducing autophagy. Sorafenib AKT serine/threonine kinase 1 Homo sapiens