Pub. Date : 2021
PMID : 33987030
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Background: Hepcidin controls iron homeostasis by inducing the degradation of the iron efflux protein, ferroportin (FPN1), and subsequently reducing serum iron levels. | Iron | hepcidin antimicrobial peptide | Mus musculus |
| 2 | Background: Hepcidin controls iron homeostasis by inducing the degradation of the iron efflux protein, ferroportin (FPN1), and subsequently reducing serum iron levels. | Iron | hepcidin antimicrobial peptide | Mus musculus |
| 3 | Background: Hepcidin controls iron homeostasis by inducing the degradation of the iron efflux protein, ferroportin (FPN1), and subsequently reducing serum iron levels. | Iron | hepcidin antimicrobial peptide | Mus musculus |
| 4 | Hepcidin expression is influenced by multiple factors, including iron stores, ineffective erythropoiesis, and inflammation. | Iron | hepcidin antimicrobial peptide | Mus musculus |
| 5 | Despite the altered expression of the aforementioned hepcidin regulators, the stimulatory effect of LPS on hepcidin mRNA expression was blunt in iron-treated Hbbth3 /+ mice. | Iron | hepcidin antimicrobial peptide | Mus musculus |
| 6 | Conclusion: Our study suggests that a hypoferremic response to LPS-induced acute inflammation is maintained in thalassemic mice with parenteral iron loading in a hepcidin-independent manner. | Iron | hepcidin antimicrobial peptide | Mus musculus |