Pub. Date : 2021 May 13
PMID : 33986418
2 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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| 1 | Two of these broad-spectrum PRL inhibitors, Salirasib and Candesartan, blocked PRL-3-induced migration in human embryonic kidney cells with no impact on cell viability. | farnesylthiosalicylic acid | protein tyrosine phosphatase 4A3 | Homo sapiens | ||
| 2 | In silico modeling revealed that Salirasib binds a putative allosteric site near the WPD loop of PRL-3, while Candesartan binds a potentially novel targetable site adjacent to the CX5R motif. | farnesylthiosalicylic acid | protein tyrosine phosphatase 4A3 | Homo sapiens | ||