Title : CircMEMO1 modulates the promoter methylation and expression of TCF21 to regulate hepatocellular carcinoma progression and sorafenib treatment sensitivity.

Pub. Date : 2021 May 13

PMID : 33985545






1 Functional Relationships(s)
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1 Mechanistic analysis revealed that circMEMO1 can modulate the promoter methylation and gene expression of TCF21 to regulate HCC progression by acting as a sponge for miR-106b-5p, which targets the TET family of genes and increases the 5hmC level. tetramethylenedisulfotetramine microRNA 106b Homo sapiens