Title : Evidence of a putative glycosaminoglycan binding site on the glycosylated SARS-CoV-2 spike protein N-terminal domain.

Pub. Date : 2021

PMID : 33968333






2 Functional Relationships(s)
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Protein Name
Organism
1 Docking studies using GlycoTorch Vina and subsequent MD simulations of the spike trimer in the presence of dodecasaccharides of the GAGs heparin and heparan sulfate supported this possibility. Heparitin Sulfate surface glycoprotein Severe acute respiratory syndrome coronavirus 2
2 These findings identify a site in the spike protein that favors heparan sulfate binding that may be particularly pertinent for a better understanding of the recent UK and South African strains. Heparitin Sulfate surface glycoprotein Severe acute respiratory syndrome coronavirus 2