Title : Altered Phase Separation and Cellular Impact in C9orf72-Linked ALS/FTD.

Pub. Date : 2021

PMID : 33967699






1 Functional Relationships(s)
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1 Evidence has now accumulated showing that the formation and function of these membraneless organelles is impaired by both the toxic arginine rich dipeptide repeat proteins (DPRs), translated from the C9orf72 repeat RNA transcript, and the repeat RNA itself. Arginine C9orf72-SMCR8 complex subunit Homo sapiens