Title : Randialic acid B and tomentosolic acid block formyl peptide receptor 1 in human neutrophils and attenuate psoriasis-like inflammation in vivo.

Pub. Date : 2021 Aug

PMID : 33964283






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In this study, we discovered two derivatives of ursolic acid, 3beta-hydroxyurs-12,18-dien-28-oic acid (randialic acid B, RAB) and 3beta-hydroxyurs-12,19-dien-28-oic acid (tomentosolic acid, TA), as FPR1 inhibitors in human neutrophils with ability to suppress psoriatic symptoms in mice. ursolic acid ArfGAP with FG repeats 1 Homo sapiens