Pub. Date : 2021 Jul
PMID : 33963018
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The results indicate that ethanol co-administered with GHB increases toxicity and MCT1 inhibition is effective in reversing toxicity by inhibiting GHB brain uptake when given post-GHB/ethanol administration. | 4-hydroxybutyric acid | solute carrier family 16 member 1 | Homo sapiens |
| 2 | The results indicate that ethanol co-administered with GHB increases toxicity and MCT1 inhibition is effective in reversing toxicity by inhibiting GHB brain uptake when given post-GHB/ethanol administration. | 4-hydroxybutyric acid | solute carrier family 16 member 1 | Homo sapiens |
| 3 | The effects of the novel MCT1 inhibitors AR-C155858 and AZD-3965 on this drug-drug interaction have not been studied before, and our preclinical studies indicate that MCT1 inhibitors can decrease brain concentrations of GHB by inhibiting brain uptake, even when administered at times after GHB/ethanol. | 4-hydroxybutyric acid | solute carrier family 16 member 1 | Homo sapiens |
| 4 | The effects of the novel MCT1 inhibitors AR-C155858 and AZD-3965 on this drug-drug interaction have not been studied before, and our preclinical studies indicate that MCT1 inhibitors can decrease brain concentrations of GHB by inhibiting brain uptake, even when administered at times after GHB/ethanol. | 4-hydroxybutyric acid | solute carrier family 16 member 1 | Homo sapiens |
| 5 | The effects of the novel MCT1 inhibitors AR-C155858 and AZD-3965 on this drug-drug interaction have not been studied before, and our preclinical studies indicate that MCT1 inhibitors can decrease brain concentrations of GHB by inhibiting brain uptake, even when administered at times after GHB/ethanol. | 4-hydroxybutyric acid | solute carrier family 16 member 1 | Homo sapiens |
| 6 | The effects of the novel MCT1 inhibitors AR-C155858 and AZD-3965 on this drug-drug interaction have not been studied before, and our preclinical studies indicate that MCT1 inhibitors can decrease brain concentrations of GHB by inhibiting brain uptake, even when administered at times after GHB/ethanol. | 4-hydroxybutyric acid | solute carrier family 16 member 1 | Homo sapiens |