Title : Exploiting the anticancer effects of a nitrogen bisphosphonate nanomedicine for glioblastoma multiforme.

Pub. Date : 2021 May 4

PMID : 33947409






3 Functional Relationships(s)
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1 In this study, a nano-formulation with the RALA peptide was used to complex the N-BP, alendronate (ALN) into nanoparticles (NPs) < 200 nm for optimal endocytic uptake. Alendronate RAS like proto-oncogene A Homo sapiens
2 In this study, a nano-formulation with the RALA peptide was used to complex the N-BP, alendronate (ALN) into nanoparticles (NPs) < 200 nm for optimal endocytic uptake. Alendronate RAS like proto-oncogene A Homo sapiens
3 RALA NPs were effectively taken up by GBM where a dose-dependent response was evidenced with potentiation factors of 14.96 and 13.4 relative to ALN alone after 72 h in LN229 and T98G cells, respectively. Alendronate RAS like proto-oncogene A Homo sapiens