Title : Transcriptional Suppression of Diabetic Nephropathy with Novel Gene Silencer Pyrrole-Imidazole Polyamides Preventing USF1 Binding to the TGF-β1 Promoter.

Pub. Date : 2021 Apr 29

PMID : 33947045






1 Functional Relationships(s)
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1 We examined the effects of synthetic pyrrole-imidazole (PI) polyamides in preventing USF1 binding on the TGF-beta1 promoter in Wistar rats in which diabetic nephropathy was established by intravenous administration of streptozotocin (STZ). Nylons upstream transcription factor 1 Rattus norvegicus