Title : The Diarylheptanoid Curcumin Induces MYC Inhibition and Cross-Links This Oncoprotein to the Coactivator TRRAP.

Pub. Date : 2021

PMID : 33937075






1 Functional Relationships(s)
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1 Curcumin-mediated covalent binding of MYC to TRRAP reduces the protein amounts of both interaction partners but does not downregulate TP53, so that the growth-arresting effect of wild type TP53 could prevail. Curcumin tumor protein p53 Homo sapiens