Title : The Key Role of NAD+ in Anti-Tumor Immune Response: An Update.

Pub. Date : 2021

PMID : 33936090






3 Functional Relationships(s)
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1 Surface CD38 expression is increased in different hematological and solid tumors, where it cooperates with other ecto-enzymes to produce the immunosuppressive molecule adenosine (ADO). Adenosine CD38 molecule Homo sapiens
2 Surface CD38 expression is increased in different hematological and solid tumors, where it cooperates with other ecto-enzymes to produce the immunosuppressive molecule adenosine (ADO). Adenosine CD38 molecule Homo sapiens
3 We therefore discuss these novel findings, examining the possible contribution of NAD+ depletion, along with ADO production, in the immunosuppressive activities of CD38 in the context of human tumors. Adenosine CD38 molecule Homo sapiens