Title : Epigenetic changes related to glucose metabolism in type 1 diabetes after BCG vaccinations: A vital role for KDM2B.

Pub. Date : 2022 Mar 8

PMID : 33933315






2 Functional Relationships(s)
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Protein Name
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1 This study unexpectedly identified both KDM2B and DDIT4 as genes controlling BCG-driven re-methylation of histones, and the activation of the mTOR pathway for facilitated glucose transport respectively. Glucose DNA damage inducible transcript 4 Homo sapiens
2 The DDIT4 gene with known inhibitory role of mTOR was re-methylated after BCG, a step likely to allow improved glucose transport. Glucose DNA damage inducible transcript 4 Homo sapiens