Pub. Date : 2021 Apr 30
PMID : 33931119
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In nonmalignant tissue, PC plays an essential role in controlling whole-body energetics through regulation of gluconeogenesis in the liver, synthesis of fatty acids in adipocytes, and insulin secretion in pancreatic beta cells. | Fatty Acids | pyruvate carboxylase | Homo sapiens |
| 2 | In breast cancer, PC activity is linked to pulmonary metastasis, potentially by providing the ability to utilize glucose, fatty acids, and glutamine metabolism as needed under varying conditions as cells metastasize. | Fatty Acids | pyruvate carboxylase | Homo sapiens |