Pub. Date : 2021 Apr 22
PMID : 33922007
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Oxaliplatin-Induced Senescence in Colorectal Cancer Cells Depends on p14ARF-Mediated Sustained p53 Activation. | Oxaliplatin | tumor protein p53 | Homo sapiens |
| 2 | Oxaliplatin treatment resulted in the G2-phase arrest in all CRC lines tested (HCT116p53+/+, HCT116p53-/-, LoVo, SW48 and SW480). | Oxaliplatin | tumor protein p53 | Homo sapiens |
| 3 | Immunoblot analysis showed that within the p53-competent lines p53 and p21CIP1 are activated at early times upon oxaliplatin treatment. | Oxaliplatin | tumor protein p53 | Homo sapiens |
| 4 | Immunoblot analysis showed that within the p53-competent lines p53 and p21CIP1 are activated at early times upon oxaliplatin treatment. | Oxaliplatin | tumor protein p53 | Homo sapiens |
| 5 | Our data show that oxaliplatin-induced senescence in CRC cells is dependent on p53 proficiency; however, a significant induction can only be observed upon p14ARF-mediated p53 stabilization. | Oxaliplatin | tumor protein p53 | Homo sapiens |
| 6 | Our data show that oxaliplatin-induced senescence in CRC cells is dependent on p53 proficiency; however, a significant induction can only be observed upon p14ARF-mediated p53 stabilization. | Oxaliplatin | tumor protein p53 | Homo sapiens |