Title : Aryl Urea Based Scaffolds for Multitarget Drug Discovery in Anticancer Immunotherapies.

Pub. Date : 2021 Apr 6

PMID : 33917617






1 Functional Relationships(s)
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1 Compounds 16 and 23 (Z) and (E)-styryl p-bromophenyl urea, respectively, showed better results than sorafenib in down-regulation of VEGFR-2 and also improved the effect of the anti-PD-L1 compound BMS-8 on both targets, PD-L1 and c-Myc proteins. Sorafenib CD274 molecule Homo sapiens