Title : Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy.

Pub. Date : 2021 Jul 31

PMID : 33915212






3 Functional Relationships(s)
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Protein Name
Organism
1 Exploring further, our in-silico analysis indicated that the heparin interacts with post-translational glycoconjugates present on spike proteins. Heparin surface glycoprotein Severe acute respiratory syndrome coronavirus 2
2 Heparin-binding to the open conformation of spike structurally supports the state and may aid ACE2 binding as reported with cell surface-bound heparan sulfate. Heparin surface glycoprotein Severe acute respiratory syndrome coronavirus 2
3 We also studied spike protein mutant variants" heparin interactions for possible resistance. Heparin surface glycoprotein Severe acute respiratory syndrome coronavirus 2