Title : Pazopanib ameliorates acute lung injuries via inhibition of MAP3K2 and MAP3K3.

Pub. Date : 2021 Apr 28

PMID : 33910977






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Pazopanib inhibits mitogen-activated protein kinase kinase kinase 2 (MAP3K2)- and MAP3K3-mediated phosphorylation of NADPH oxidase 2 subunit p47phox at Ser208 to increase reactive oxygen species (ROS) formation in myeloid cells. Reactive Oxygen Species cytochrome b-245 beta chain Homo sapiens
2 Pazopanib inhibits mitogen-activated protein kinase kinase kinase 2 (MAP3K2)- and MAP3K3-mediated phosphorylation of NADPH oxidase 2 subunit p47phox at Ser208 to increase reactive oxygen species (ROS) formation in myeloid cells. Reactive Oxygen Species cytochrome b-245 beta chain Homo sapiens