Title : Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity.

Pub. Date : 2021 Aug

PMID : 33909257






1 Functional Relationships(s)
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1 Mechanistically, bavachin specifically increases the production of nigericin-induced mitochondrial reactive oxygen species among the most important upstream events in the activation of the NLRP3 inflammasome. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens