Pub. Date : 2021 Jun
PMID : 33907837
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Importantly, we noted that treatment with a Notch signaling inhibitor DAPT produced very similar anticancer efficacy in both HepG2 and Huh-7 cell lines, and administration of DAPT also efficiently suppressed HepG2 xenograft outgrowth. | dapt | notch receptor 1 | Homo sapiens |
| 2 | Importantly, we noted that treatment with a Notch signaling inhibitor DAPT produced very similar anticancer efficacy in both HepG2 and Huh-7 cell lines, and administration of DAPT also efficiently suppressed HepG2 xenograft outgrowth. | dapt | notch receptor 1 | Homo sapiens |
| 3 | To this end, we anticipated that AB4 and DAPT may act on the same signaling pathway, probably through inhibition of the Notch pathway. | dapt | notch receptor 1 | Homo sapiens |