Title : The heat shock response, determined by QuantiGene multiplex, is impaired in HD mouse models and not caused by HSF1 reduction.

Pub. Date : 2021 Apr 27

PMID : 33907289






1 Functional Relationships(s)
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1 Huntington"s disease (HD) is a devastating neurodegenerative disorder, caused by a CAG/polyglutamine repeat expansion, that results in the aggregation of the huntingtin protein, culminating in the deposition of inclusion bodies in HD patient brains. polyglutamine huntingtin Homo sapiens