Pub. Date : 2021 May 11
PMID : 33903171
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Interestingly, the glycans at two glycosylation sites, N90 and N322, have opposite effects on spike protein binding. | Polysaccharides | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
2 | Therefore, this glycan can interfere with the binding of the spike protein and protect against docking of the virus to the cell. | Polysaccharides | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
3 | By contrast, the glycan at the N322 site interacts tightly with the RBD of the ACE2-bound spike protein and strengthens the complex. | Polysaccharides | surface glycoprotein | Severe acute respiratory syndrome coronavirus 2 |