Title : Curcumin-loaded liposomes with the hepatic and lysosomal dual-targeted effects for therapy of hepatocellular carcinoma.

Pub. Date : 2021 Jun 1

PMID : 33892061






3 Functional Relationships(s)
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1 Because galactose group can recognize ASGPR overexpressed on hepatoma cells and morpholine group can target to the lysosome, they are integrated into a dual-targeted lipid material with low toxicity. Galactose asialoglycoprotein receptor 1 Homo sapiens
2 The endocytosis of Gal-Mor-LPs was competitively inhibited by galactose, which confirmed the galactose modified liposomes entered hepatoma cells via ASGPR-mediated pathway. Galactose asialoglycoprotein receptor 1 Homo sapiens
3 The endocytosis of Gal-Mor-LPs was competitively inhibited by galactose, which confirmed the galactose modified liposomes entered hepatoma cells via ASGPR-mediated pathway. Galactose asialoglycoprotein receptor 1 Homo sapiens